Chemical genomics is the identification of new drugs and drug targets by screening small molecule libraries.
Approaches
You can use a forward (classical) approach or a reverse approach. In forward chemical genomics you study a phenotype and identify small molecules that interact with the function of interest. In reverse chemical genomics you start with a known enzyme and test different chemicals that may alter the enzymes function in order to confirm the specific role the enzyme plays in a biological response.
Applications
Applications of chemical genomics include identifying novel drug targets, identifying genes involved in a specific bio-activity, and identifying modes of action.
Conclusion
Unfortunately at this time PubChem did not have a sufficient amount of data regarding ptk7 targets, bio-assays, or bio-activities related to bone formation in scoliosis.
Reference [1] Wuster A, Madan Babu M (May 2008). "Chemogenomics and biotechnology". Trends in Biotechnology. 26 (5): 252–8.